Illustration of problem of False positives
and False negatives when testing for HIV antibody.

TEST

Positive Negative Totals
Disease Present Sensitivity False -  
  Not Present False+ Specificity  

TEST

Positive Negative Totals
Disease Present 196 4 200
  Not Present 19996 979804 999800
Totals 20192 979808 1,000,000

 

Prevalence = 2/1000, Sensitivity = 0.98, Specificity = 0.98

 

What can you deduce about the ability to provide useful information by mass testing a population for a rare disease e.g. all poeple applying for a marriage license for HIV?